Changes in Marrow Adipose Tissue in Relation to Changes in Bone Parameters Following Estradiol Replacement in Adolescent and Young Adult Females with Functional Hypothalamic Amenorrhea

CONTEXT: Low energy availability causes disruption of hypothalamic gonadotropin-releasing hormone secretion leading to functional hypothalamic amenorrhea (FHA) and hypoestrogenism, which in turn contributes to decreased bone mineral density (BMD) and increased bone marrow adipose tissue (MAT). Trans...

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Pubblicato in:Bone
Autori principali: Singhal, Vibha, Karzar, Nazanin Hazhir, Bose, Amita, Buckless, Colleen, Ackerman, Kathryn E, Bredella, Miriam A., Klibanski, Anne, Misra, Madhusmita
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8022869/
https://ncbi.nlm.nih.gov/pubmed/33418100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2021.115841
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