Complement-5 Inhibition Deters Progression of Fulminant Hepatitis to Acute Liver Failure in Murine Models

BACKGROUND & AIMS: Acute liver failure (ALF) is a life-threatening condition with limited treatment alternatives. ALF pathogenesis seemingly involves the complement system. However, no complement-targeted intervention has been clinically applied. In this study, we aimed to investigate the potent...

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Dades bibliogràfiques
Publicat a:Cell Mol Gastroenterol Hepatol
Autors principals: Kusakabe, Jiro, Hata, Koichiro, Miyauchi, Hidetaka, Tajima, Tetsuya, Wang, Yi, Tamaki, Ichiro, Kawasoe, Junya, Okamura, Yusuke, Zhao, Xiangdong, Okamoto, Tatsuya, Tsuruyama, Tatsuaki, Uemoto, Shinji
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2021
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8022253/
https://ncbi.nlm.nih.gov/pubmed/33444818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2021.01.001
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