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Reconciling VEGF With VPF: The Importance of Increased Vascular Permeability for Stroma Formation in Tumors, Healing Wounds, and Chronic Inflammation

It is widely believed that vascular endothelial growth factor (VEGF) induces angiogenesis by its direct mitogenic and motogenic actions on vascular endothelial cells. However, these activities are only detected when endothelial cells are cultured at very low (0.1%) serum concentrations and would not...

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Bibliographic Details
Published in:Front Cell Dev Biol
Main Author: Dvorak, Harold F.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8021773/
https://ncbi.nlm.nih.gov/pubmed/33834026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.660609
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