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pH-Responsive Amphiphilic Carboxylate Polymers: Design and Potential for Endosomal Escape
The intracellular delivery of emerging biomacromolecular therapeutics, such as genes, peptides, and proteins, remains a great challenge. Unlike small hydrophobic drugs, these biotherapeutics are impermeable to the cell membrane, thus relying on the endocytic pathways for cell entry. After endocytosi...
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| Pubblicato in: | Front Chem |
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| Autore principale: | |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8021698/ https://ncbi.nlm.nih.gov/pubmed/33834015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2021.645297 |
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