Sphingosine-kinase-1 expression is associated with improved overall survival in high-grade serous ovarian cancer

PURPOSE: Sphingosine-kinase-1 (SPHK1) is a key enzyme of sphingolipid metabolism which is involved in ovarian cancer pathogenesis, progression and mechanisms of drug resistance. It is overexpressed in a variety of cancer subtypes. We investigated SPHK1 expression as a prognostic factor in epithelial...

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Publicat a:J Cancer Res Clin Oncol
Autors principals: Hanker, L. C., El-Balat, A., Drosos, Z., Kommoss, S., Karn, T., Holtrich, U., Gitas, G., Graeser-Mayer, M., Anglesio, M., Huntsman, D., Rody, A., Gevensleben, H., Hoellen, F.
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2021
Matèries:
Original Article – Cancer Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8021516/
https://ncbi.nlm.nih.gov/pubmed/33660008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00432-021-03558-x
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