Preclinical development of a molecular clamp‐stabilised subunit vaccine for severe acute respiratory syndrome coronavirus 2

OBJECTIVES: Efforts to develop and deploy effective vaccines against severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) continue at pace. Here, we describe rational antigen design through to manufacturability and vaccine efficacy of a prefusion‐stabilised spike (S) protein, Sclamp, in comb...

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Detaylı Bibliyografya
Yayımlandı:Clin Transl Immunology
Asıl Yazarlar: Watterson, Daniel, Wijesundara, Danushka K, Modhiran, Naphak, Mordant, Francesca L, Li, Zheyi, Avumegah, Michael S, McMillan, Christopher LD, Lackenby, Julia, Guilfoyle, Kate, van Amerongen, Geert, Stittelaar, Koert, Cheung, Stacey TM, Bibby, Summa, Daleris, Mallory, Hoger, Kym, Gillard, Marianne, Radunz, Eve, Jones, Martina L, Hughes, Karen, Hughes, Ben, Goh, Justin, Edwards, David, Scoble, Judith, Pearce, Lesley, Kowalczyk, Lukasz, Phan, Tram, La, Mylinh, Lu, Louis, Pham, Tam, Zhou, Qi, Brockman, David A, Morgan, Sherry J, Lau, Cora, Tran, Mai H, Tapley, Peter, Villalón‐Letelier, Fernando, Barnes, James, Young, Andrew, Jaberolansar, Noushin, Scott, Connor AP, Isaacs, Ariel, Amarilla, Alberto A, Khromykh, Alexander A, van den Brand, Judith MA, Reading, Patrick C, Ranasinghe, Charani, Subbarao, Kanta, Munro, Trent P, Young, Paul R, Chappell, Keith J
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2021
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Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8021130/
https://ncbi.nlm.nih.gov/pubmed/33841880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cti2.1269
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