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Sexually dimorphic placental responses to maternal SARS-CoV-2 infection

There is a persistent male bias in the prevalence and severity of COVID-19 disease. Underlying mechanisms accounting for this sex difference remain incompletely understood. Interferon responses have been implicated as a modulator of disease in adults, and play a key role in the placental anti-viral...

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Pubblicato in:bioRxiv
Autori principali: Bordt, Evan A, Shook, Lydia L, Atyeo, Caroline, Pullen, Krista M, De Guzman, Rose M, Meinsohn, Marie-Charlotte, Chauvin, Maeva, Fischinger, Stephanie, Yockey, Laura J., James, Kaitlyn, Lima, Rosiane, Yonker, Lael M, Fasano, Alessio, Brigida, Sara, Bebell, Lisa M, Roberts, Drucilla J, Pépin, David, Huh, Jun R, Bilbo, Staci D, Li, Jonathan Z, Kaimal, Anjali, Schust, Danny, Gray, Kathryn J, Lauffenburger, Douglas, Alter, Galit, Edlow, Andrea G
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8020979/
https://ncbi.nlm.nih.gov/pubmed/33821279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.03.29.437516
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