Mitochondrial metabolism is essential for invariant natural killer T cell development and function

Conventional T cell fate and function are determined by coordination between cellular signaling and mitochondrial metabolism. Invariant natural killer T (iNKT) cells are an important subset of “innate-like” T cells that exist in a preactivated effector state, and their dependence on mitochondrial me...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Weng, Xiufang, Kumar, Amrendra, Cao, Liang, He, Ying, Morgun, Eva, Visvabharathy, Lavanya, Zhao, Jie, Sena, Laura A., Weinberg, Sam E., Chandel, Navdeep S., Wang, Chyung-Ru
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8020658/
https://ncbi.nlm.nih.gov/pubmed/33753493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2021385118
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