Activated nanoscale actin-binding domain motion in the catenin–cadherin complex revealed by neutron spin echo spectroscopy

As the core component of the adherens junction in cell–cell adhesion, the cadherin–catenin complex transduces mechanical tension between neighboring cells. Structural studies have shown that the cadherin–catenin complex exists as an ensemble of flexible conformations, with the actin-binding domain (...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: Farago, Bela, Nicholl, Iain D., Wang, Shen, Cheng, Xiaolin, Callaway, David J. E., Bu, Zimei
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2021
Ämnen:
Physical Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8020631/
https://ncbi.nlm.nih.gov/pubmed/33753508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2025012118
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