Exposure to p40 in Early Life Prevents Intestinal Inflammation in Adulthood Through Inducing a Long-Lasting Epigenetic Imprint on TGFβ

BACKGROUND & AIMS: Colonization by gut microbiota in early life confers beneficial effects on immunity throughout the host’s lifespan. We sought to elucidate the mechanisms whereby neonatal supplementation with p40, a probiotic functional factor, reprograms intestinal epithelial cells for protec...

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Detalhes bibliográficos
Publicado no:Cell Mol Gastroenterol Hepatol
Main Authors: Deng, Yilin, McDonald, Oliver G., Means, Anna L., Peek, Richard M., Washington, M. Kay, Acra, Sari A., Polk, D. Brent, Yan, Fang
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8020481/
https://ncbi.nlm.nih.gov/pubmed/33482393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2021.01.004
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