Microneedle patch for the ultrasensitive quantification of protein biomarkers in interstitial fluid

The detection and quantification of protein biomarkers in interstitial fluid (ISF) is hampered by challenges in its sampling and analysis. Here, we report a microneedle patch for the fast in vivo sampling and on-needle quantification of target protein biomarkers in ISF. We used plasmonic fluor — an...

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Veröffentlicht in:Nat Biomed Eng
Hauptverfasser: Wang, Zheyu, Luan, Jingyi, Seth, Anushree, Liu, Lin, You, Minli, Gupta, Prashant, Rathi, Priya, Wang, Yixuan, Cao, Sisi, Jiang, Qisheng, Zhang, Xiao, Gupta, Rohit, zhou, Qingjun, Morrissey, Jeremiah J., Scheller, Erica L, Rudra, Jai S, Singamaneni, Srikanth
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8020465/
https://ncbi.nlm.nih.gov/pubmed/33483710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41551-020-00672-y
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