Dexmedetomidine Attenuates Ischemia/Reperfusion-Induced Myocardial Inflammation and Apoptosis Through Inhibiting Endoplasmic Reticulum Stress Signaling

BACKGROUND: Endoplasmic reticulum stress (ERS)-mediated myocardial inflammation and apoptosis plays an important role in myocardial ischemia/reperfusion (I/R) injury. Dexmedetomidine has been used clinically with sedative, analgesic, and anti-inflammatory properties. This study aimed to determine th...

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Detalhes bibliográficos
Publicado no:J Inflamm Res
Main Authors: Yang, Yu-fan, Wang, Hui, Song, Nan, Jiang, Ya-hui, Zhang, Jun, Meng, Xiao-wen, Feng, Xiao-mei, Liu, Hong, Peng, Ke, Ji, Fu-hai
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2021
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8020464/
https://ncbi.nlm.nih.gov/pubmed/33833544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JIR.S292263
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