20(S)-protopanaxadiol and oleanolic acid ameliorate cognitive deficits in APP/PS1 transgenic mice by enhancing hippocampal neurogenesis

BACKGROUND: Alzheimer's disease (AD) is one of the most prevalent neurodegenerative disorders. Enhancing hippocampal neurogenesis by promoting proliferation and differentiation of neural stem cells (NSCs) is a promising therapeutic strategy for AD. 20(S)-protopanaxadiol (PPD) and oleanolic acid...

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Detalhes bibliográficos
Publicado no:J Ginseng Res
Main Authors: Lin, Kaili, Sze, Stephen Cho-Wing, Liu, Bin, Zhang, Zhang, Zhang, Zhu, Zhu, Peili, Wang, Ying, Deng, Qiudi, Yung, Ken Kin-Lam, Zhang, Shiqing
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8020272/
https://ncbi.nlm.nih.gov/pubmed/33841013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jgr.2020.07.003
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