Osthole Attenuates Macrophage Activation in Experimental Asthma by Inhibitingthe NF-ĸB/MIF Signaling Pathway

Inhibition of activated macrophages is an alternative therapeutic strategy for asthma. We investigated whether a coumarin compound, osthole, isolated from Cnidium monnieri (L.) Cuss, alleviated macrophage activation in vivo and in vitro. Osthole could reduce expression of a marker of activated macro...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Li, Ruyi, Song, Peng, Tang, Guofang, Wei, Jianghong, Rao, Lizong, Ma, Libing, Jiang, Ming, Huang, Jianwei, Xu, Qing, Wu, Jingjie, Lv, Qian, Yao, Dong, Xiao, Bo, Huang, Haiming, Lei, Liping, Feng, Juntao, Mo, Biwen
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8020258/
https://ncbi.nlm.nih.gov/pubmed/33828480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.572463
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