Triptolide inhibits JAK2/STAT3 signaling and induces lethal autophagy through ROS generation in cisplatin-resistant SKOV3/DDP ovarian cancer cells

Advanced and recurrent ovarian cancer has a poor prognosis and is frequently resistant to numerous therapeutics; thus, safe and effective drugs are needed to combat this disease. Previous studies have demonstrated that triptolide (TPL) exhibits anticancer and sensitization effects against cisplatin...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Oncol Rep
Autori principali: Zhong, Yanying, Le, Fuyin, Cheng, Jiao, Luo, Chen, Zhang, Xiali, Wu, Xingwu, Xu, Fang, Zuo, Qi, Tan, Buzhen
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2021
Soggetti:
Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8020210/
https://ncbi.nlm.nih.gov/pubmed/33760192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2021.8020
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi