Intracisternal administration of tanshinone IIA-loaded nanoparticles leads to reduced tissue injury and functional deficits in a porcine model of ischemic stroke

BACKGROUND: The absolute number of new stroke patients is annually increasing and there still remains only a few Food and Drug Administration (FDA) approved treatments with significant limitations available to patients. Tanshinone IIA (Tan IIA) is a promising potential therapeutic for ischemic strok...

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Bibliografiska uppgifter
I publikationen:IBRO Neurosci Rep
Huvudupphovsmän: Waters, Elizabeth S., Kaiser, Erin E., Yang, Xueyuan, Fagan, Madison M., Scheulin, Kelly M., Jeon, Julie H., Shin, Soo K., Kinder, Holly A., Kumar, Anil, Platt, Simon R., Duberstein, Kylee J., Park, Hea Jin, Xie, Jin, West, Franklin D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2021
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8019951/
https://ncbi.nlm.nih.gov/pubmed/33842909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ibneur.2020.11.003
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