Intracisternal administration of tanshinone IIA-loaded nanoparticles leads to reduced tissue injury and functional deficits in a porcine model of ischemic stroke

BACKGROUND: The absolute number of new stroke patients is annually increasing and there still remains only a few Food and Drug Administration (FDA) approved treatments with significant limitations available to patients. Tanshinone IIA (Tan IIA) is a promising potential therapeutic for ischemic strok...

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Gepubliceerd in:IBRO Neurosci Rep
Hoofdauteurs: Waters, Elizabeth S., Kaiser, Erin E., Yang, Xueyuan, Fagan, Madison M., Scheulin, Kelly M., Jeon, Julie H., Shin, Soo K., Kinder, Holly A., Kumar, Anil, Platt, Simon R., Duberstein, Kylee J., Park, Hea Jin, Xie, Jin, West, Franklin D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2021
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Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8019951/
https://ncbi.nlm.nih.gov/pubmed/33842909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ibneur.2020.11.003
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