miR-135a Reduces Osteosarcoma Pulmonary Metastasis by Targeting Both BMI1 and KLF4

Because of the modest response rate after surgery and chemotherapy, treatment of osteosarcoma (OS) remains challenging due to tumor recurrence and metastasis. miR-135a has been reported to act as an anticarcinogenic regulator of several cancers. However, its expression and function in osteosarcoma r...

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Bibliographic Details
Published in:Front Oncol
Main Authors: Chen, Chenglong, Mao, Xingjia, Cheng, Caitong, Jiao, Yurui, Zhou, Yi, Ren, Tingting, Wu, Zhuangzhuang, Lv, Zhi, Sun, Xiaojuan, Guo, Wei
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
Subjects:
Oncology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8019936/
https://ncbi.nlm.nih.gov/pubmed/33828977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.620295
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