Transient Astrocytic Gq Signaling Underlies Remote Memory Enhancement

Astrocytes elicit transient Ca(2+) elevations induced by G protein-coupled receptors (GPCRs), yet their role in vivo remains unknown. To address this, transgenic mice with astrocytic expression of the optogenetic Gq-type GPCR, Optoα1AR, were established, in which transient Ca(2+) elevations similar...

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Bibliographische Detailangaben
Veröffentlicht in:Front Neural Circuits
Hauptverfasser: Iwai, Youichi, Ozawa, Katsuya, Yahagi, Kazuko, Mishima, Tsuneko, Akther, Sonam, Vo, Camilla Trang, Lee, Ashley Bomin, Tanaka, Mika, Itohara, Shigeyoshi, Hirase, Hajime
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Neuroscience
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8019746/
https://ncbi.nlm.nih.gov/pubmed/33828463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncir.2021.658343
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