Functional and Activation Profiles of Mucosal-Associated Invariant T Cells in Patients With Tuberculosis and HIV in a High Endemic Setting

Background: MAIT cells are non-classically restricted T lymphocytes that recognize and rapidly respond to microbial metabolites or cytokines and have the capacity to kill bacteria-infected cells. Circulating MAIT cell numbers generally decrease in patients with active TB and HIV infection, but findi...

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Enregistré dans:
Détails bibliographiques
Publié dans:Front Immunol
Auteurs principaux: Balfour, Avuyonke, Schutz, Charlotte, Goliath, Rene, Wilkinson, Katalin A., Sayed, Sumaya, Sossen, Bianca, Kanyik, Jean-Paul, Ward, Amy, Ndzhukule, Rhandzu, Gela, Anele, Lewinsohn, David M., Lewinsohn, Deborah A., Meintjes, Graeme, Shey, Muki
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2021
Sujets:
Immunology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8019701/
https://ncbi.nlm.nih.gov/pubmed/33828558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.648216
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