Nucleolin-Targeting AS1411 Aptamer-Modified Micelle for the Co-Delivery of Doxorubicin and miR-519c to Improve the Therapeutic Efficacy in Hepatocellular Carcinoma Treatment

BACKGROUND: Multidrug resistance (MDR) has emerged to be a major hindrance in cancer therapy, which contributes to the reduced sensitivity of cancer cells toward chemotherapeutic drugs mainly owing to the over-expression of drug efflux transporters. The combination of gene therapy and chemotherapy h...

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Bibliografiske detaljer
Udgivet i:Int J Nanomedicine
Main Authors: Liang, Xiao, Wang, Yudi, Shi, Hui, Dong, Mengmeng, Han, Haobo, Li, Quanshun
Format: Artigo
Sprog:Inglês
Udgivet: Dove 2021
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8019667/
https://ncbi.nlm.nih.gov/pubmed/33833512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S304526
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