Spatial learning and memory deficits induced by prenatal glucocorticoid exposure depend on hippocampal CRHR1 and CXCL5 signaling in rats

BACKGROUND: Prenatal synthetic glucocorticoid (sGC) exposure increases the susceptibility to cognitive and affective disorders in postnatal life. We previously demonstrated that prenatal sGC exposure results in an increase in corticotropin-releasing hormone (CRH) receptor type 1 (CRHR1) expression i...

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Bibliografiske detaljer
Udgivet i:J Neuroinflammation
Main Authors: Zheng, You, Zhang, Yan-Min, Tang, Zheng-Shan, Du, Jian-Kui, Guo, De-Wei, Xu, Yong-Jun, Sheng, Hui, Lu, Jian-Qiang, Ni, Xin
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8019183/
https://ncbi.nlm.nih.gov/pubmed/33810797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-021-02129-8
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