טוען...
Optimized Ring Closing Metathesis Reaction Conditions to Suppress Desallyl Side Products in the Solid Phase Synthesis of Cyclic Peptides involving Tyrosine(O-allyl)
We are exploring constraining aromatic residues in the kappa opioid receptor selective antagonist arodyn (Ac[Phe(1,2,3),Arg(4),D-Ala(8)]dynorphin A(1–11)-NH(2)) by ring closing metathesis (RCM) involving tyrosine(O-allyl) (Tyr(All)), but desallyl products limited the yields of the desired cyclic pep...
שמור ב:
| הוצא לאור ב: | J Org Chem |
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| Main Authors: | , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2020
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8018726/ https://ncbi.nlm.nih.gov/pubmed/31880448 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.9b02345 |
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