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A Framework and Case Studies for Evaluation of Enzyme Ontogeny in Children’s Health Risk Evaluation

Knowledge of the ontogeny of Phase I and Phase II metabolizing enzymes could be used to inform children’s vulnerability based upon likely differences in internal dose from xenobiotic exposure. This can provide a qualitative assessment of toxicokinetic variability and uncertainty pertinent to early l...

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Bibliografski detalji
Izdano u:J Toxicol Environ Health A
Glavni autori: Ginsberg, Gary, Vulimiri, Suryanarayana V., Lin, Yu-Sheng, Kancherla, Jayaram, Foos, Brenda, Sonawane, Babasaheb
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8018602/
https://ncbi.nlm.nih.gov/pubmed/28891786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15287394.2017.1369915
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