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Identifying hydrophobic protein patches to inform protein interaction interfaces

Interactions between proteins lie at the heart of numerous biological processes and are essential for the proper functioning of the cell. Although the importance of hydrophobic residues in driving protein interactions is universally accepted, a characterization of protein hydrophobicity, which infor...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Rego, Nicholas B., Xi, Erte, Patel, Amish J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8018078/
https://ncbi.nlm.nih.gov/pubmed/33526682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2018234118
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