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Iron accumulation in the choroid plexus, ependymal cells and CNS parenchyma in a rat strain with low‐grade haemolysis of fragile macrocytic red blood cells

Iron accumulation in the CNS is associated with many neurological diseases via amplification of inflammation and neurodegeneration. However, experimental studies on iron overload are challenging, since rodents hardly accumulate brain iron in contrast to humans. Here, we studied LEWzizi rats, which p...

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Detalhes bibliográficos
Publicado no:Brain Pathol
Main Authors: Wimmer, Isabella, Scharler, Cornelia, Kadowaki, Taro, Hillebrand, Sophie, Scheiber‐Mojdehkar, Barbara, Ueda, Shuichi, Bradl, Monika, Berger, Thomas, Lassmann, Hans, Hametner, Simon
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8018038/
https://ncbi.nlm.nih.gov/pubmed/33220123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12920
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