HNRNPA2B1 promotes multiple myeloma progression by increasing AKT3 expression via m6A-dependent stabilization of ILF3 mRNA

N6-methyladenosine (m6A) modification is the most prevalent modification in eukaryotic RNAs while accumulating studies suggest that m6A aberrant expression plays an important role in cancer. HNRNPA2B1 is a m6A reader which binds to nascent RNA and thus affects a perplexing array of RNA metabolism ex...

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Detalhes bibliográficos
Publicado no:J Hematol Oncol
Main Authors: Jiang, Fengjie, Tang, Xiaozhu, Tang, Chao, Hua, Zhen, Ke, Mengying, Wang, Chen, Zhao, Jiamin, Gao, Shengyao, Jurczyszyn, Artur, Janz, Siegfried, Beksac, Meral, Zhan, Fenghuang, Gu, Chunyan, Yang, Ye
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Letter to the Editor
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8017865/
https://ncbi.nlm.nih.gov/pubmed/33794982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-021-01066-6
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