Arsenic trioxide replacing or reducing chemotherapy in consolidation therapy for acute promyelocytic leukemia (APL2012 trial)

As all-trans retinoic acid (ATRA) and arsenic trioxide (ATO) are widely accepted in treating acute promyelocytic leukemia (APL), deescalating toxicity becomes a research hotspot. Here, we evaluated whether chemotherapy could be replaced or reduced by ATO in APL patients at different risks. After ach...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Chen, Li, Zhu, Hong-Ming, Li, Yan, Liu, Qi-Fa, Hu, Yu, Zhou, Jian-Feng, Jin, Jie, Hu, Jian-Da, Liu, Ting, Wu, De-Pei, Chen, Jie-Ping, Lai, Yong-Rong, Wang, Jian-Xiang, Li, Juan, Li, Jian-Yong, Du, Xin, Wang, Xin, Yang, Ming-Zhen, Yan, Jin-Song, Ouyang, Gui-Fang, Liu, Li, Hou, Ming, Huang, Xiao-Jun, Yan, Xiao-Jing, Xu, Dan, Li, Wei-Ming, Li, Deng-Ju, Lou, Yin-Jun, Wu, Zheng-Jun, Niu, Ting, Wang, Ying, Li, Xiao-Yang, You, Jian-Hua, Zhao, Hui-Jin, Chen, Yú, Shen, Yang, Chen, Qiu-Sheng, Chen, Yù, Li, Jian, Wang, Bing-Shun, Zhao, Wei-Li, Mi, Jian-Qing, Wang, Kan-Kan, Hu, Jiong, Chen, Zhu, Chen, Sai-Juan, Li, Jun-Min
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8017727/
https://ncbi.nlm.nih.gov/pubmed/33495363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2020382118
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