ALDH1A1 Genetic Variations May Modulate Risk of Parkinson’s Disease in Han Chinese Population

Background: Studies in animal models have suggested that aldehyde dehydrogenase 1 (encoded by ALDH1A1) protects against Parkinson’s disease (PD) by reducing toxic metabolites of dopamine. Herein we aimed to investigate whether ALDH1A1 was genetically associated with PD susceptibility in humans. Meth...

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Vydáno v:Front Neurosci
Hlavní autoři: Fan, Hui-Hui, Guo, Qing, Zheng, Jing, Lian, Yi-Zhi, Huang, Shi-Shi, Sun, Yue, Zou, Ming, Zhu, Jian-Hong, Zhang, Xiong
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8017280/
https://ncbi.nlm.nih.gov/pubmed/33815038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2021.620929
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