Evolution of DNA methylation in the human brain

DNA methylation is a critical regulatory mechanism implicated in development, learning, memory, and disease in the human brain. Here we have elucidated DNA methylation changes during recent human brain evolution. We demonstrate dynamic evolutionary trajectories of DNA methylation in cell-type and cy...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Jeong, Hyeonsoo, Mendizabal, Isabel, Berto, Stefano, Chatterjee, Paramita, Layman, Thomas, Usui, Noriyoshi, Toriumi, Kazuya, Douglas, Connor, Singh, Devika, Huh, Iksoo, Preuss, Todd M., Konopka, Genevieve, Yi, Soojin V.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8017017/
https://ncbi.nlm.nih.gov/pubmed/33795684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21917-7
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