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Utidelone inhibits growth of colorectal cancer cells through ROS/JNK signaling pathway

Utidelone (UTD1), a novel microtubule stabilizing agent, is an epothilone B analogue which was produced by genetic engineering. UTD1 has exhibited broad antitumor activity in multiple solid tumors. However, its activity and mechanism in colorectal cancer (CRC) remain to be studied. In this study, UT...

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Bibliografische gegevens
Gepubliceerd in:Cell Death Dis
Hoofdauteurs: Li, Fuli, Huang, Tinglei, Tang, Yao, Li, Qingli, Wang, Jianzheng, Cheng, Xiaojiao, Zhang, Wenhui, Zhang, Baiwen, Zhou, Cong, Tu, Shuiping
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8016927/
https://ncbi.nlm.nih.gov/pubmed/33795638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03619-6
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