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Suppression of TGF-β1 signaling by Matrigel via FAK signaling in cultured human trabecular meshwork cells

The trabecular meshwork (TM) is composed of TM cells and beams of the extracellular matrix, together contributing to aqueous humor (AH) outflow resistance. Herein, we validated that our culture system on 2D Matrigel expressed putative TM markers and myocilin, of which the latter was upregulated by d...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhang, Yuan, Tseng, Scheffer C. G., Zhu, Ying-Ting
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8016910/
https://ncbi.nlm.nih.gov/pubmed/33795740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-86591-7
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