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Wnt5a promotes hippocampal postsynaptic development and GluN2B-induced expression via the eIF2α HRI kinase

Wnt signaling plays a key role in neurodevelopment and neuronal maturation. Specifically, Wnt5a stimulates postsynaptic assemblies, increases glutamatergic neurotransmission and, through calcium signaling, generates nitric oxide (NO). Trying to unveil the molecular pathway triggering these postsynap...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ramos-Fernández, Eva, Arrázola, Macarena S., Oliva, Carolina A., Arredondo, Sebastián B., Varela-Nallar, Lorena, Inestrosa, Nibaldo C.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8016897/
https://ncbi.nlm.nih.gov/pubmed/33795747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-86708-y
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