APOE alleles’ association with cognitive function differs across Hispanic/Latino groups and genetic ancestry in the study of Latinos‐investigation of neurocognitive aging (HCHS/SOL)

INTRODUCTION: Apolipoprotein E (APOE) alleles are associated with cognitive decline, mild cognitive impairment (MCI), and Alzheimer's disease in Whites, but have weaker and inconsistent effects reported in Latinos. We hypothesized that this heterogeneity is due to ancestry‐specific genetic effe...

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Bibliografiska uppgifter
I publikationen:Alzheimers Dement
Huvudupphovsmän: Granot‐Hershkovitz, Einat, Tarraf, Wassim, Kurniansyah, Nuzulul, Daviglus, Martha, Isasi, Carmen R., Kaplan, Robert, Lamar, Melissa, Perreira, Krista M., Wassertheil‐Smoller, Sylvia, Stickel, Ariana, Thyagarajan, Bharat, Zeng, Donglin, Fornage, Myriam, DeCarli, Charles S., González, Hector M., Sofer, Tamar
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2020
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8016734/
https://ncbi.nlm.nih.gov/pubmed/33155766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/alz.12205
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