APOE alleles’ association with cognitive function differs across Hispanic/Latino groups and genetic ancestry in the study of Latinos‐investigation of neurocognitive aging (HCHS/SOL)

INTRODUCTION: Apolipoprotein E (APOE) alleles are associated with cognitive decline, mild cognitive impairment (MCI), and Alzheimer's disease in Whites, but have weaker and inconsistent effects reported in Latinos. We hypothesized that this heterogeneity is due to ancestry‐specific genetic effe...

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Bibliografske podrobnosti
izdano v:Alzheimers Dement
Main Authors: Granot‐Hershkovitz, Einat, Tarraf, Wassim, Kurniansyah, Nuzulul, Daviglus, Martha, Isasi, Carmen R., Kaplan, Robert, Lamar, Melissa, Perreira, Krista M., Wassertheil‐Smoller, Sylvia, Stickel, Ariana, Thyagarajan, Bharat, Zeng, Donglin, Fornage, Myriam, DeCarli, Charles S., González, Hector M., Sofer, Tamar
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2020
Teme:
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8016734/
https://ncbi.nlm.nih.gov/pubmed/33155766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/alz.12205
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