Data-driven noise modeling of digital DNA melting analysis enables prediction of sequence discriminating power

MOTIVATION: The need to rapidly screen complex samples for a wide range of nucleic acid targets, like infectious diseases, remains unmet. Digital High-Resolution Melt (dHRM) is an emerging technology with potential to meet this need by accomplishing broad-based, rapid nucleic acid sequence identific...

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Foilsithe in:Bioinformatics
Main Authors: Langouche, Lennart, Aralar, April, Sinha, Mridu, Lawrence, Shelley M, Fraley, Stephanie I, Coleman, Todd P
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2020
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Original Papers
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8016452/
https://ncbi.nlm.nih.gov/pubmed/33355665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa1053
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