Moringa isothiocyanate-1 regulates Nrf2 and NF-κB pathway in response to LPS-driven sepsis and inflammation

This study aims to document the dual mode of pharmacological action of moringa isothiocyanate-1 (MIC-1) derived from seeds of Moringa oleifera Lam. Oral administration of chemically stable MIC-1 (80 mg/kg) significantly reduced the expression of inflammatory markers (Tnf-α, Ifn-α, IL-1β, IL-6) in th...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Sailaja, Badi Sri, Aita, Rohit, Maledatu, Shane, Ribnicky, David, Verzi, Michael P., Raskin, Ilya
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2021
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8016325/
https://ncbi.nlm.nih.gov/pubmed/33793581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0248691
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