DNA hypo-methylation facilitates anti-inflammatory responses in severe ulcerative colitis

Severe ulcerative colitis (UC) is a potentially life-threatening disease with a potential colorectal cancer (CRC) risk. The aim of this study was to explore the relationship between transcriptomic and genome-wide DNA methylation profiles in a well-stratified, treatment-naïve severe UC patient popula...

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Udgivet i:PLoS One
Main Authors: Taman, Hagar, Fenton, Christopher G., Anderssen, Endre, Florholmen, Jon, Paulssen, Ruth H.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8016308/
https://ncbi.nlm.nih.gov/pubmed/33793617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0248905
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