CD40 signaling augments IL-10 expression and the tolerogenicity of IL-10-induced regulatory dendritic cells

CD40 expressed on stimulatory dendritic cells (DC) provides an important accessory signal for induction of effector T cell responses. It is also expressed at lower levels on regulatory DC (DCreg), but there is little evidence that CD40 signaling contributes to the tolerogenic activity of these cells...

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Pubblicato in:PLoS One
Autori principali: Dawicki, Wojciech, Huang, Hui, Ma, Yanna, Town, Jennifer, Zhang, Xiaobei, Rudulier, Chris D., Gordon, John R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2021
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8016274/
https://ncbi.nlm.nih.gov/pubmed/33793599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0248290
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