Transient receptor potential channel TRPV4 mediates TGF-β1-induced differentiation of human ventricular fibroblasts

BACKGROUND: Cardiac fibroblasts (CFs) are principal extracellular matrix-producing cells. In response to injury, CFs transdifferentiate into myofibroblasts. Intracellular calcium (Ca(2+)) signaling, involved in fibroblast proliferation and differentiation, is activated in fibroblasts through transie...

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Detalhes bibliográficos
Publicado no:Cardiol J
Main Authors: Ahn, Min-Soo, Eom, Young Woo, Oh, Ji-Eun, Cha, Seung-Kuy, Park, Kyu Sang, Son, Jung-Woo, Lee, Jun-Won, Youn, Young Jin, Ahn, Sung Gyun, Kim, Jang-Young, Lee, Seung-Hwan, Yoon, Junghan, Yoo, Byung-Su
Formato: Artigo
Idioma:Inglês
Publicado em: Via Medica 2020
Assuntos:
Basic Science and Experimental Cardiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8016025/
https://ncbi.nlm.nih.gov/pubmed/32329036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5603/CJ.a2019.0050
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