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Cellular plasticity balances the metabolic and proliferation dynamics of a regenerating liver

The adult liver has an exceptional ability to regenerate, but how it maintains its specialized functions during regeneration is unclear. Here, we used partial hepatectomy (PHx) in tandem with single-cell transcriptomics to track cellular transitions and heterogeneities of ∼22,000 liver cells through...

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Bibliografiske detaljer
Udgivet i:Genome Res
Main Authors: Chembazhi, Ullas V., Bangru, Sushant, Hernaez, Mikel, Kalsotra, Auinash
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8015853/
https://ncbi.nlm.nih.gov/pubmed/33649154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.267013.120
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