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Cellular plasticity balances the metabolic and proliferation dynamics of a regenerating liver

The adult liver has an exceptional ability to regenerate, but how it maintains its specialized functions during regeneration is unclear. Here, we used partial hepatectomy (PHx) in tandem with single-cell transcriptomics to track cellular transitions and heterogeneities of ∼22,000 liver cells through...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Chembazhi, Ullas V., Bangru, Sushant, Hernaez, Mikel, Kalsotra, Auinash
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8015853/
https://ncbi.nlm.nih.gov/pubmed/33649154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.267013.120
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