Mutant p53 regulates Survivin to foster lung metastasis

Esophageal squamous cell carcinoma (ESCC) is one of the most lethal cancers worldwide and evolves often to lung metastasis. P53(R175H) (homologous to Trp53(R172H) in mice) is a common hot spot mutation. How metastasis is regulated by p53(R175H) in ESCC remains to be investigated. To investigate p53(...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Tang, Qiaosi, Efe, Gizem, Chiarella, Anna M., Leung, Jessica, Chen, Maoting, Yamazoe, Taiji, Su, Zhenyi, Pitarresi, Jason R., Li, Jinyang, Islam, Mirazul, Karakasheva, Tatiana, Klein-Szanto, Andres J., Pan, Samuel, Hu, Jianhua, Natsugoe, Shoji, Gu, Wei, Stanger, Ben Z., Wong, Kwok-K, Diehl, J. Alan, Bass, Adam J., Nakagawa, Hiroshi, Murphy, Maureen E., Rustgi, Anil K.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2021
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8015716/
https://ncbi.nlm.nih.gov/pubmed/33737385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.340505.120
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