Defining the signalling determinants of a posterior ventral spinal cord identity in human neuromesodermal progenitor derivatives

The anteroposterior axial identity of motor neurons (MNs) determines their functionality and vulnerability to neurodegeneration. Thus, it is a crucial parameter in the design of strategies aiming to produce MNs from human pluripotent stem cells (hPSCs) for regenerative medicine/disease modelling app...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Wind, Matthew, Gogolou, Antigoni, Manipur, Ichcha, Granata, Ilaria, Butler, Larissa, Andrews, Peter W., Barbaric, Ivana, Ning, Ke, Guarracino, Mario R., Placzek, Marysia, Tsakiridis, Anestis
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2021
Assuntos:
Human Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8015249/
https://ncbi.nlm.nih.gov/pubmed/33658223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.194415
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