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Groucho co-repressor proteins regulate β cell development and proliferation by repressing Foxa1 in the developing mouse pancreas

Groucho-related genes (GRGs) are transcriptional co-repressors that are crucial for many developmental processes. Several essential pancreatic transcription factors are capable of interacting with GRGs; however, the in vivo role of GRG-mediated transcriptional repression in pancreas development is s...

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Publicado en:Development
Main Authors: Theis, Alexandra, Singer, Ruth A., Garofalo, Diana, Paul, Alexander, Narayana, Anila, Sussel, Lori
Formato: Artigo
Idioma:Inglês
Publicado: The Company of Biologists Ltd 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8015241/
https://ncbi.nlm.nih.gov/pubmed/33658226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.192401
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