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SEC24A facilitates colocalization and Ca(2)(+) flux between the endoplasmic reticulum and mitochondria
A genome-wide screen recently identified SEC24A as a novel mediator of thapsigargin-induced cell death in HAP1 cells. Here, we determined the cellular mechanism and specificity of SEC24A-mediated cytotoxicity. Measurement of Ca(2+) levels using organelle-specific fluorescent indicator dyes showed th...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Cell Sci |
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| Κύριοι συγγραφείς: | , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
The Company of Biologists Ltd
2021
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8015215/ https://ncbi.nlm.nih.gov/pubmed/33622772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.249276 |
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