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Convenient Novel Method to Access N-Benzylated Isatoic Anhydride: Reaction Behavior of Isatoic Anhydride with 4-Chlorobenzyl Chloride in the Presence of Bases

[Image: see text] Sodium hydride, potassium carbonate, and other bases are commonly used for N-alkylation of heterocyclic compounds. This report reveals the problems associated with N-benzylation of isatoic anhydride and identifies the plausible byproduct structures formed during the reaction. Subse...

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Publié dans:ACS Omega
Auteurs principaux: Verma, Ekta, Patil, Shailendra, Gajbhiye, Asmita
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2021
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8015103/
https://ncbi.nlm.nih.gov/pubmed/33817495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.1c00061
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