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Endothelial-derived exosomes induced by lipopolysaccharide alleviate rat cardiomyocytes injury and apoptosis

Sepsis-induced myocardial dysfunction (SIMD) is one of the leading causes of death in sepsis. We hypothesized that exosomes released from ECs exposed to bacterial lipopolysaccharides (LPS) have some regulatory effect on cardiomyocytes (CMs). In this study, cultured rat ECs were exposed to 0.5 µg/ml...

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Detalles Bibliográficos
Publicado en:Am J Transl Res
Autores principales: Cao, Yu, Wang, Yan, Xiao, Ling, Xu, Jia-Ying, Liu, Ying, Jiang, Rui, Li, Tao, Jiang, Jun
Formato: Artigo
Lenguaje:Inglês
Publicado: e-Century Publishing Corporation 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8014340/
https://ncbi.nlm.nih.gov/pubmed/33841668
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