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Deprotection of centromeric cohesin at meiosis II requires APC/C activity but not kinetochore tension
Genome haploidization involves sequential loss of cohesin from chromosome arms and centromeres during two meiotic divisions. At centromeres, cohesin's Rec8 subunit is protected from separase cleavage at meiosis I and then deprotected to allow its cleavage at meiosis II. Protection of centromeri...
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| Publicado no: | EMBO J |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8013787/ https://ncbi.nlm.nih.gov/pubmed/33644894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020106812 |
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