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Deprotection of centromeric cohesin at meiosis II requires APC/C activity but not kinetochore tension
Genome haploidization involves sequential loss of cohesin from chromosome arms and centromeres during two meiotic divisions. At centromeres, cohesin's Rec8 subunit is protected from separase cleavage at meiosis I and then deprotected to allow its cleavage at meiosis II. Protection of centromeri...
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| Publicado en: | EMBO J |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8013787/ https://ncbi.nlm.nih.gov/pubmed/33644894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020106812 |
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