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Depolarizing GABA(A) current in the prefrontal cortex is linked with cognitive impairment in a mouse model relevant for schizophrenia
Cognitive impairment in schizophrenia (CIAS) is the most critical predictor of functional outcome. Limited understanding of the cellular mechanisms of CIAS hampers development of more effective treatments. We found that in subchronic phencyclidine (scPCP)–treated mice, an animal model that mimics CI...
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| Publicado no: | Sci Adv |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Association for the Advancement of Science
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8011979/ https://ncbi.nlm.nih.gov/pubmed/33789887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aba5032 |
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