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Loss of chromatin structural integrity is a source of stress during aging

Dysfunction and dysregulation at multiple levels, from organismal to molecular, are associated with the biological process of aging. In a eukaryotic nucleus, multiple lines of evidence have shown that the fundamental structure of chromatin is affected by aging. Not only euchromatic and heterochromat...

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Pubblicato in:Hum Genet
Autori principali: Yu, Ruofan, McCauley, Brenna, Dang, Weiwei
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8011432/
https://ncbi.nlm.nih.gov/pubmed/31900586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-019-02100-x
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