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Characterization and discovery of a selective small molecule modulator of mitochondrial complex I targeting a unique binding site
Mitochondrial dysfunction has been recognized as an essential contributor to many human diseases including neurodegenerative disorders. However, the exact pathological role of mitochondrial dysfunction, especially for mitochondrial reactive oxygen species associated oxidative stress, remains elusive...
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| Udgivet i: | J Med Chem |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8011337/ https://ncbi.nlm.nih.gov/pubmed/32945676 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.0c01021 |
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