The Brain-Derived Neurotrophic Factor Val66Met Polymorphism Can Protect Against Cognitive Impairment in Multiple Sclerosis

Introduction: Brain-derived neurotrophic factor (BDNF) is a member of the neurotrophin family, involved in neuronal survival and synaptic plasticity. The BDNF Val66Met polymorphism is known to reduce BDNF expression and secretion; its role in multiple sclerosis (MS) is poorly investigated. Objective...

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Veröffentlicht in:Front Neurol
Hauptverfasser: Portaccio, Emilio, Bellinvia, Angelo, Prestipino, Elio, Nacmias, Benedetta, Bagnoli, Silvia, Razzolini, Lorenzo, Pastò, Luisa, Niccolai, Claudia, Goretti, Benedetta, Fonderico, Mattia, Zimatore, Giovanni Bosco, Losignore, Nunzia Alessandra, Sorbi, Sandro, Amato, Maria Pia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Neurology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8011315/
https://ncbi.nlm.nih.gov/pubmed/33815257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2021.645220
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